rs2277598

A SNP in the BBS4 gene on chromosome 15. Its most notable genotype is T;T: common in clinvar

Gene
BBS4
Location
Chr 1572,735,137 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
45%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TMost notableGoodcommon in clinvarTypical · 0.038% of people
  2. C;CNot ratedNo summary available.Typical · 0.019% of people

SNPedia records rs2277598 on the minus strand: (A;A), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageT;T 38% C;C 19%
  • European ancestry (Utah)T;T 10% C;C 46%
  • Han Chinese (Beijing)T;T 57% C;C 5%
  • Japanese (Tokyo)T;T 56% C;C <1%
  • Yoruba (Nigeria)T;T 54% C;C 7%
  • African ancestry (Southwest US)T;T 47% C;C 14%
  • Chinese (Denver)T;T 52% C;C 7%
  • Gujarati IndianT;T 19% C;C 39%
  • Luhya (Kenya)T;T 51% C;C 6%
  • Mexican ancestry (Los Angeles)T;T 14% C;C 36%
  • Maasai (Kenya)T;T 44% C;C 8%
  • TuscanT;T 10% C;C 36%

Other BBS4 SNPs

All BBS4 SNPs

Source and license

Adapted from rs2277598 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.