rs2280838
A SNP in the SLC39A4 gene on chromosome 8. Its most notable genotype is C;C: common in clinvar
- Gene
- SLC39A4
- Location
- Chr 8144,416,618 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 48%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs2280838 on the minus strand: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageC;C 32%
- European ancestry (Utah)C;C 25%
- Han Chinese (Beijing)C;C 29%
- Japanese (Tokyo)C;C 36%
- Yoruba (Nigeria)C;C 37%
- African ancestry (Southwest US)C;C 25%
- Chinese (Denver)C;C 36%
- Gujarati IndianC;C 42%
- Luhya (Kenya)C;C 37%
- Mexican ancestry (Los Angeles)C;C 36%
- Maasai (Kenya)C;C 31%
- TuscanC;C 20%
Related
Other SLC39A4 SNPs
- rs121434287A;GCarrier of an acrodermatitis enteropathica mutationImportant
- rs121434288C;TCarrier of an acrodermatitis enteropathica mutationImportant
- rs121434289C;TCarrier of an acrodermatitis enteropathica mutationImportant
- rs121434290G;TCarrier of an acrodermatitis enteropathica mutationImportant
- rs121434291C;TCarrier of an acrodermatitis enteropathica mutationImportant
- rs121434292A;GCarrier of an acrodermatitis enteropathica mutationImportant
- rs121434293C;GCarrier of an acrodermatitis enteropathica mutationImportant
- rs782695425-;GCarrier of a likely acrodermatitis enteropathica mutationImportant
Source and license
Adapted from rs2280838 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.