rs2298668

A SNP in the PRCP gene on chromosome 11. Its most notable genotype is T;T: common in complete genomics

Gene
PRCP
Location
Chr 1182,853,252 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, FamilyTreeDNA
Minor allele frequency
14%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TMost notableGoodcommon in complete genomicsTypical · 0.087% of people

SNPedia records rs2298668 on the minus strand: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 4 HapMap populations.

  • AverageT;T 87%
  • European ancestry (Utah)T;T 82%
  • Han Chinese (Beijing)T;T 89%
  • Japanese (Tokyo)T;T 91%
  • Yoruba (Nigeria)T;T 86%

Conditions, medicines and genes

Notes

From SNPedia

Notes

Women with the snp has been linked to significant risk of a premature birth These press releases explain it more simply The risky variation is 3x more common in women of african descent. *rs2298668 Prolylcarboxypepdiase E112D (rs2298668)D allele alone and jointly with chronic hypertension were associated with a significantly increased risk of preeclampsia Polymorphism in maternal LRP8 gene is associated with fetal growth.

Source and license

Adapted from rs2298668 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.