rs2300478(G;T)

1.7x risk for developing restless legs syndrome

Magnitude
1.5Minor
Repute
Bad
Frequency
34%Average of 11 populations
On SNPedia
rs2300478(G;T)
Gene
MEIS1

Frequency

Share of people with G;T in each HapMap population.

  • Tuscan50%
  • Gujarati Indian47%
  • Japanese (Tokyo)43%
  • European ancestry (Utah)40%
  • Han Chinese (Beijing)40%
  • Chinese (Denver)39%
  • Mexican ancestry (Los Angeles)38%
  • Luhya (Kenya)25%
  • African ancestry (Southwest US)23%
  • Yoruba (Nigeria)20%
  • Maasai (Kenya)15%

Other genotypes of rs2300478

  1. A;ANot ratedNo summary available.Typical · 0.00% of people
  2. G;GMost notableBad>1.7x risk for developing restless legs syndromeWorth knowing · 2.03% of people
  3. T;TGoodNormal risk of developing restless legs syndromeMinor · 1.062% of people

All about rs2300478

Notes

From SNPedia

Variants in MEIS1 rs2300478, BTBD9 rs9357271, and MAP2K5/SKOR1 rs1026732 confer a significant risk of RLS in a US population. Association studies of variants in MEIS1, BTBD9, and MAP2K5/SKOR1 with restless legs syndrome in a US population.

References

Source and license

Adapted from rs2300478(G;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.