rs2301436

A SNP in the FGFR1OP gene on chromosome 6. Its most notable genotype is T;T.

Gene
FGFR1OP
Location
Chr 6167,024,500 (GRCh38)
Highest magnitude
2.1Worth knowing
Tested on
23andMe, AncestryDNA
Minor allele frequency
39%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TMost notableBadNo summary available.Worth knowing · 2.116% of people
  2. C;CGoodNo summary available.Typical · 0.039% of people

SNPedia records rs2301436 on the minus strand: (A;A), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageT;T 16% C;C 39%
  • European ancestry (Utah)T;T 26% C;C 35%
  • Han Chinese (Beijing)T;T 12% C;C 34%
  • Japanese (Tokyo)T;T 12% C;C 40%
  • Yoruba (Nigeria)T;T 10% C;C 37%
  • African ancestry (Southwest US)T;T 18% C;C 42%
  • Chinese (Denver)T;T 16% C;C 42%
  • Gujarati IndianT;T 15% C;C 41%
  • Luhya (Kenya)T;T 7% C;C 52%
  • Mexican ancestry (Los Angeles)T;T 22% C;C 43%
  • Maasai (Kenya)T;T 10% C;C 40%
  • TuscanT;T 24% C;C 24%

Conditions, medicines and genes

Notes

From SNPedia

Notes

DeCode reports that rs2301436 is associated with susceptibility to Crohn's disease.

Source and license

Adapted from rs2301436 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.