rs2306374

A SNP in the MRAS gene on chromosome 3. Its most notable genotype is C;C: Increased risk for CHD

Gene
MRAS
Location
Chr 3138,401,110 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
8%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableBadIncreased risk for CHDTypical · 0.0<1% of people

On SNPedia: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 10 HapMap populations.

  • AverageC;C <1%
  • European ancestry (Utah)C;C 2%
  • Han Chinese (Beijing)C;C 0%
  • Japanese (Tokyo)C;C 0%
  • Yoruba (Nigeria)C;C 0%
  • African ancestry (Southwest US)C;C 0%
  • Gujarati IndianC;C 0%
  • Luhya (Kenya)C;C 0%
  • Mexican ancestry (Los Angeles)C;C 0%
  • Maasai (Kenya)C;C 0%
  • TuscanC;C 0%

Conditions, medicines and genes

Notes

From SNPedia

Notes

23andMe blog coronary artery disease and heart attack SNP Risk Version Effect *rs646776 T 1.19 *rs17465637 C 1.14 *rs1746048 C 1.17 *rs6725887 C 1.17 *rs11206510 T 1.15 *rs3184504 T 1.13 *rs2306374 C 1.15 *rs3782886 C 1.44 Coronary Heart Disease

Source and license

Adapted from rs2306374 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.