rs2393903

A SNP in the ZNF365 gene on chromosome 10. Its most notable genotype is T;T: normal

Gene
ZNF365
Location
Chr 1062,620,576 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TMost notableGoodnormalTypical · 0.014% of people
  2. C;TBad1.2x increased risk for atopic dermatitisTypical · 0.039% of people
  3. C;CBad1.37x increased risk for atopic dermatitisTypical · 0.047% of people

SNPedia records rs2393903 on the minus strand: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageT;T 14% C;T 39% C;C 47%
  • European ancestry (Utah)T;T 20% C;T 46% C;C 35%
  • Han Chinese (Beijing)T;T 37% C;T 41% C;C 22%
  • Japanese (Tokyo)T;T 10% C;T 56% C;C 35%
  • Yoruba (Nigeria)T;T 0% C;T 5% C;C 95%
  • African ancestry (Southwest US)T;T 4% C;T 23% C;C 74%
  • Chinese (Denver)T;T 36% C;T 46% C;C 18%
  • Gujarati IndianT;T 14% C;T 54% C;C 33%
  • Luhya (Kenya)T;T 0% C;T 26% C;C 74%
  • Mexican ancestry (Los Angeles)T;T 9% C;T 43% C;C 48%
  • Maasai (Kenya)T;T 3% C;T 31% C;C 66%
  • TuscanT;T 25% C;T 55% C;C 21%

Source and license

Adapted from rs2393903 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.