rs2412541

A SNP in the KNL1 gene on chromosome 15. Its most notable genotype is G;G: common in clinvar

Gene
KNL1
Location
Chr 1540,621,642 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
34%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. G;GMost notableGoodcommon in clinvarTypical · 0.019% of people
  2. T;TNot ratedNo summary available.Typical · 0.042% of people

On SNPedia: (G;G), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageG;G 19% T;T 42%
  • European ancestry (Utah)G;G 2% T;T 72%
  • Han Chinese (Beijing)G;G 50% T;T 7%
  • Japanese (Tokyo)G;G 44% T;T 11%
  • Yoruba (Nigeria)G;G 10% T;T 58%
  • African ancestry (Southwest US)G;G 7% T;T 54%
  • Chinese (Denver)G;G 43% T;T 13%
  • Gujarati IndianG;G 9% T;T 45%
  • Luhya (Kenya)G;G 12% T;T 49%
  • Mexican ancestry (Los Angeles)G;G 21% T;T 25%
  • Maasai (Kenya)G;G 5% T;T 55%
  • TuscanG;G 4% T;T 78%

Source and license

Adapted from rs2412541 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.