rs2547231

A SNP in the SULT2A1 gene on chromosome 19. Its most notable genotype is C;C: Decreased levels of some blood metabolites

Gene
SULT2A1
Location
Chr 1947,881,800 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA, FamilyTreeDNA

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. C;CMost notableNot ratedDecreased levels of some blood metabolitesWorth knowing · 2.0<1% of people
  2. A;ANot ratedIncreased blood metabolite levelsWorth knowing · 2.085% of people

SNPedia records rs2547231 on the minus strand: (G;G), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C <1% A;A 85%
  • European ancestry (Utah)C;C 2% A;A 64%
  • Han Chinese (Beijing)C;C 0% A;A 99%
  • Japanese (Tokyo)C;C 0% A;A 100%
  • Yoruba (Nigeria)C;C <1% A;A 81%
  • African ancestry (Southwest US)C;C 0% A;A 84%
  • Chinese (Denver)C;C 0% A;A 99%
  • Gujarati IndianC;C 1% A;A 78%
  • Luhya (Kenya)C;C 0% A;A 84%
  • Mexican ancestry (Los Angeles)C;C 0% A;A 83%
  • Maasai (Kenya)C;C 1% A;A 87%
  • TuscanC;C 4% A;A 73%

Notes

From SNPedia

Notes

C;C

PMID 24816252

A;A

5alpha-androstan-3beta,17beta-diol disulfate - 0.081 unit increase X-12850 - 0.059 unit increase X-12456 - 0.041 unit increase X-11440/4-androsten-3beta,17beta-diol disulfate 2 - 0.141 unit increase

References

Source and license

Adapted from rs2547231 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.