rs254942

A SNP in the ERCC4 gene on chromosome 16. Its most notable genotype is G;G: common in clinvar

Gene
ERCC4
Location
Chr 1613,932,150 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
7%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GMost notableGoodcommon in clinvarTypical · 0.02% of people
  2. A;AGoodcommon genotypeTypical · 0.085% of people

SNPedia records rs254942 on the minus strand: (C;C), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 9 HapMap populations.

  • AverageG;G 2% A;A 85%
  • European ancestry (Utah)G;G <1% A;A 94%
  • Han Chinese (Beijing)G;G 5% A;A 57%
  • Japanese (Tokyo)G;G 4% A;A 65%
  • Yoruba (Nigeria)G;G 0% A;A 100%
  • Chinese (Denver)G;G 6% A;A 64%
  • Gujarati IndianG;G 0% A;A 97%
  • Mexican ancestry (Los Angeles)G;G 0% A;A 97%
  • Maasai (Kenya)G;G 0% A;A 98%
  • TuscanG;G 0% A;A 92%

Other ERCC4 SNPs

All ERCC4 SNPs

Source and license

Adapted from rs254942 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.