rs25531(T;T)

Short form of 5-HTTLPR. lower levels of serotonin, slightly less happy, benefits from more support

Magnitude
2.5Worth knowing
Repute
Not rated
On SNPedia
rs25531(A;A)Minus strand
Gene
SLC6A4

Other genotypes of rs25531

  1. -;-Not ratedNo summary available.Typical · 0.0
  2. C;CNot ratedlong form of 5-HTTLPR. less sensitive to painWorth knowing · 2.1

All about rs25531

Notes

From SNPedia

23andMe reports that this genotype is not reliable on their platform. 23andMe users should ignore this result. This genotype is associated with lower levels of serotonin and appears to have a cognitive effect related to emotions, but the effect is slight and no one in SNPedia has yet found a good description. However the (G;G) genotype generally seems to have more positive associations, while this (A;A) is more negative. Examples of the differences include biased attention for negative word stimuli and gaze bias for emotional information. More reluctant to endorse utilitarian actions resulting in foreseen harm to an innocent individual The genotype of this SNP is not meaningful on 23andme v3. *https://www.23andme.com/you/community/thread/6192/

References

Source and license

Adapted from rs25531(A;A) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.