rs2572886

A SNP on chromosome 8. Its most notable genotype is A;A: 1.4x increased risk of HIV infection

Gene
None listed
Location
Chr 8142,821,739 (GRCh38)
Highest magnitude
2.1Worth knowing
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
14%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableBad1.4x increased risk of HIV infectionWorth knowing · 2.14% of people
  2. A;GBad1.4x increased risk of HIV infectionWorth knowing · 2.029% of people
  3. G;GGoodnormalTypical · 0.067% of people

On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 4% A;G 29% G;G 67%
  • European ancestry (Utah)A;A 0% A;G 14% G;G 86%
  • Han Chinese (Beijing)A;A 6% A;G 29% G;G 65%
  • Japanese (Tokyo)A;A 8% A;G 40% G;G 52%
  • Yoruba (Nigeria)A;A 8% A;G 32% G;G 60%
  • African ancestry (Southwest US)A;A 0% A;G 40% G;G 60%
  • Chinese (Denver)A;A 6% A;G 44% G;G 51%
  • Gujarati IndianA;A 0% A;G 14% G;G 86%
  • Luhya (Kenya)A;A 4% A;G 34% G;G 63%
  • Mexican ancestry (Los Angeles)A;A 0% A;G 26% G;G 74%
  • Maasai (Kenya)A;A 8% A;G 35% G;G 57%
  • TuscanA;A 0% A;G 13% G;G 87%

Conditions, medicines and genes

Notes

From SNPedia

Notes

rs2572886 is a SNP determined by both linkage studies and in-vitro experiments to increase the susceptibility to infection by HIV. The risk allele, rs2572886(A), yields an odds ratio of 1.4 (p=0.001), and also appears to be associated with higher viral load and faster disease progression. blog

Source and license

Adapted from rs2572886 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.