rs2630578

An association regarding telomere length with a p-value of (1.9x10^(-5)), stated that people carrying the minor allele 'C' at rs2630578 have telomeres within their white blood cells (leukocytes) that are on average 604 (+/-204) base pairs shorter than people who carry the common 'GG' genotype at this SNP. The authors estimate that this size of a difference between telomere length is equivalent to having cells which have comparatively gone through an additional "15-20 years of age-related attrition", however, no actual effects on aging or health were associated with this SNP in the study. As rs2630578 was genotyped by both the v3 & v4 chips, it should be in 23andMe's database for the majority of their customers, however, if this specific location was not genotyped or returned a 'No Call' or similar non-result - it may still be possible to determine your genotype by using the direct substitute rs2668301. This is possible because, as made apparent by comparing the population frequencies of the two SNPs, they are in very close linkage with one another within most human populations. Meaning, the 'T' version of rs2668301 is equivalent to having the 'G' version of rs2630578, and the 'C' alleles for both SNPs are equivalent to each other.)