rs2653349(A;G)

~1.5x? increased risk for cluster headaches

Magnitude
0.0Typical
Repute
Bad
Frequency
19%Average of 11 populations
On SNPedia
rs2653349(A;G)
Gene
HCRTR2

Frequency

Share of people with A;G in each HapMap population.

  • European ancestry (Utah)28%
  • Tuscan28%
  • African ancestry (Southwest US)26%
  • Gujarati Indian25%
  • Luhya (Kenya)22%
  • Mexican ancestry (Los Angeles)21%
  • Yoruba (Nigeria)20%
  • Chinese (Denver)16%
  • Han Chinese (Beijing)13%
  • Maasai (Kenya)8%
  • Japanese (Tokyo)7%

Other genotypes of rs2653349

  1. A;ANot ratednormalTypical · 0.01% of people
  2. G;GMost notableBad2-6x increased risk for cluster headachesMinor · 1.180% of people

All about rs2653349

Source and license

Adapted from rs2653349(A;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.