rs2707466

A SNP in the WNT16 gene on chromosome 7. Its most notable genotype is T;T: stronger bones

Gene
WNT16
Location
Chr 7121,339,035 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
47%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TMost notableGoodstronger bonesWorth knowing · 2.037% of people
  2. C;CBadweaker bonesWorth knowing · 2.032% of people

SNPedia records rs2707466 on the minus strand: (A;A), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageT;T 37% C;C 32%
  • European ancestry (Utah)T;T 17% C;C 35%
  • Han Chinese (Beijing)T;T 5% C;C 69%
  • Japanese (Tokyo)T;T 4% C;C 71%
  • Yoruba (Nigeria)T;T 82% C;C 1%
  • African ancestry (Southwest US)T;T 70% C;C 2%
  • Chinese (Denver)T;T 4% C;C 72%
  • Gujarati IndianT;T 22% C;C 31%
  • Luhya (Kenya)T;T 84% C;C 3%
  • Mexican ancestry (Los Angeles)T;T 30% C;C 32%
  • Maasai (Kenya)T;T 61% C;C 7%
  • TuscanT;T 22% C;C 26%

Conditions, medicines and genes

Notes

From SNPedia

Notes

Osteoporosis

Source and license

Adapted from rs2707466 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.