rs2814778(C;C)

Duffy-negative, Fy(a-b-) phenotype; resistance to malaria;, increased odds of HIV infection upon exposure, but slowed disease progression if infected

Magnitude
1.0Minor
Repute
Good
Frequency
50%Average of 5 populations
On SNPedia
rs2814778(G;G)Minus strand
Gene
DARC

Frequency

Share of people with C;C in each HapMap population.

  • Luhya (Kenya)99%
  • Maasai (Kenya)87%
  • African ancestry (Southwest US)63%
  • Mexican ancestry (Los Angeles)0%
  • Tuscan0%

Other genotypes of rs2814778

  1. T;TMost notableGoodDuffy-positiveMinor · 1.039% of people
  2. C;TGoodDuffy-positiveMinor · 1.011% of people

All about rs2814778

Notes

From SNPedia

See discussion and citations at rs2814778; this is the major Duffy phenotype found in Africans and African-Americans.

Source and license

Adapted from rs2814778(G;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.