rs2820037

A SNP on chromosome 1. Its most notable genotype is A;A: normal

Gene
None listed
Location
Chr 1239,273,242 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
18%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableNot ratednormalTypical · 0.065% of people
  2. A;TBad1.5x risk of high blood pressureTypical · 0.027% of people
  3. T;TBad1.1x risk of high blood pressureTypical · 0.08% of people

On SNPedia: (A;A), (A;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 65% A;T 27% T;T 8%
  • European ancestry (Utah)A;A 69% A;T 25% T;T 6%
  • Han Chinese (Beijing)A;A 86% A;T 13% T;T <1%
  • Japanese (Tokyo)A;A 89% A;T 11% T;T <1%
  • Yoruba (Nigeria)A;A 35% A;T 48% T;T 18%
  • African ancestry (Southwest US)A;A 53% A;T 35% T;T 12%
  • Chinese (Denver)A;A 89% A;T 10% T;T <1%
  • Gujarati IndianA;A 75% A;T 21% T;T 4%
  • Luhya (Kenya)A;A 42% A;T 46% T;T 13%
  • Mexican ancestry (Los Angeles)A;A 72% A;T 21% T;T 7%
  • Maasai (Kenya)A;A 40% A;T 39% T;T 21%
  • TuscanA;A 68% A;T 30% T;T 2%

Conditions, medicines and genes

Notes

From SNPedia

Notes

rs2820037 has been reported in a large study to be associated with high blood pressure. The risk allele (oriented to the dbSNP entry) is (T); the odds ratio associated with heterozygotes is 1.54 (CI 1.03-2.31), and for homozygotes, 1.09 (CI 0.74-1.62). Replication of the Wellcome Trust genome-wide association study of essential hypertension: the Family Blood Pressure Program. Using a latent growth curve model for an integrative assessment of the effects of genetic and environmental factors on multiple phenotypes.

Source and license

Adapted from rs2820037 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.