rs28363394
A SNP in the CTNNA1 gene on chromosome 5. Its most notable genotype is C;C: common in clinvar
- Gene
- CTNNA1
- Location
- Chr 5138,812,250 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- FamilyTreeDNA
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 4 HapMap populations.
- AverageC;C 99%
- European ancestry (Utah)C;C 99%
- Han Chinese (Beijing)C;C 99%
- Mexican ancestry (Los Angeles)C;C 98%
- TuscanC;C 99%
Related
Conditions, medicines and genes
Notes
From SNPedia
Notes
Exome Sequencing of Familial Bipolar Disorder. The minor allele of this SNP is one of 84 rare variants speculated to have an impact (positive or negative; see publication for specific SNP details) on risk for bipolar disorder. The analysis of many more patients is likely to be required to confirm or refute this association.
Source and license
Adapted from rs28363394 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.