rs28756991

A SNP in the MLH3 gene on chromosome 14. Its most notable genotype is C;C: common in complete genomics

Gene
MLH3
Location
Chr 1475,047,266 (GRCh38)
Highest magnitude
0.0Typical
Tested on
Not on consumer chips
Minor allele frequency
2%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. C;CMost notableGoodcommon in complete genomicsTypical · 0.091% of people

SNPedia records rs28756991 on the minus strand: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 9 HapMap populations.

  • AverageC;C 91%
  • European ancestry (Utah)C;C 97%
  • Yoruba (Nigeria)C;C 80%
  • African ancestry (Southwest US)C;C 86%
  • Chinese (Denver)C;C 98%
  • Gujarati IndianC;C 98%
  • Luhya (Kenya)C;C 79%
  • Mexican ancestry (Los Angeles)C;C 90%
  • Maasai (Kenya)C;C 92%
  • TuscanC;C 99%

Other MLH3 SNPs

All MLH3 SNPs

Source and license

Adapted from rs28756991 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.