rs28909980
A SNP in the CHEK2 gene on chromosome 22. Its most notable genotype is C;C: common in clinvar
- Gene
- CHEK2
- Location
- Chr 2228,696,957 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs28909980 on the minus strand: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 7 HapMap populations.
- AverageC;C 98%
- European ancestry (Utah)C;C 99%
- Han Chinese (Beijing)C;C 99%
- Japanese (Tokyo)C;C 97%
- Yoruba (Nigeria)C;C 99%
- Chinese (Denver)C;C 99%
- Luhya (Kenya)C;C 98%
- Mexican ancestry (Los Angeles)C;C 95%
Related
Other CHEK2 SNPs
- rs121908702A;CBreast cancer associated mutationVery important
- rs137853007A;GBreast cancer associated mutationVery important
- rs587780183-;ABreast cancer associated mutationVery important
- rs587780184-;ABreast cancer associated mutationVery important
- rs587780186-;CBreast cancer associated mutationVery important
- rs587781269A;GBreast cancer associated mutationVery important
- rs587781592A;GBreast cancer associated mutationVery important
- rs587781699C;TBreast cancer associated mutationVery important
Source and license
Adapted from rs28909980 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.