rs28940871(C;C)

23andMe = Tay-Sachs disease likely, but on other platforms this may be the normal form

Magnitude
5.0Very important
Repute
Not rated
On SNPedia
rs28940871(G;G)Minus strand
Gene
HEXA

Other genotypes of rs28940871

  1. G;GGoodcommon in clinvarTypical · 0.0
  2. C;GBadCarrier of a Tay-Sachs mutationImportant · 3.0

All about rs28940871

Notes

From SNPedia

This position is an ambiguous flip which seems to have been flipped between b36 and b37. 23andMe users who see GG at the 23andMe site, are normal. However using more recent dbSNP based data, (G;G) is the risk genotype. Tay-Sachs disease likely; see details

Source and license

Adapted from rs28940871(G;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.