rs2967605

A SNP in the RAB11B gene on chromosome 19. Its most notable genotype is C;C.

Gene
RAB11B
Location
Chr 198,404,854 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
31%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. C;CMost notableNot ratedNo summary available.Typical · 0.050% of people

SNPedia records rs2967605 on the minus strand: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 50%
  • European ancestry (Utah)C;C 68%
  • Han Chinese (Beijing)C;C 17%
  • Japanese (Tokyo)C;C 21%
  • Yoruba (Nigeria)C;C 56%
  • African ancestry (Southwest US)C;C 58%
  • Chinese (Denver)C;C 15%
  • Gujarati IndianC;C 55%
  • Luhya (Kenya)C;C 65%
  • Mexican ancestry (Los Angeles)C;C 60%
  • Maasai (Kenya)C;C 71%
  • TuscanC;C 65%

Conditions, medicines and genes

Notes

From SNPedia

Show notes, about 200 words

per the 23andMe blog, the minor allele of this SNP (T) was associated with decreased HDL cholesterol {| border="1" |- !SNP !Rarer allele !LDL !HDL !TG |- | rs6544713 || T || + || || |- | rs2650000 || A || + || || |- | rs471364 || C || || - || |- | rs1800961 || T || || - || |- | rs7679 || C || || - || + |- | rs2967605 || T || || - || |- | rs2409722 || T || || || - |- | rs10903129 || A || - || - || - |- | rs6756629 || A || - || + || - |- | rs12670798 || C || + || + || + |- | rs7395662 || A || - || + || + |- | rs174570 || T || - || - || + |- | rs2271293 || A || - || + || - |- | rs2624265 || C || || || + |- | rs2167079 || T || || + || |- | rs9891572 || T || || + || |- | rs4844614 || T || + || || |- | rs5031002 || G || + || || |- |} Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease. Investigation of variants identified in caucasian genome-wide association studies for plasma high-density lipoprotein cholesterol and triglycerides levels in Mexican dyslipidemic study samples. Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC).

Source and license

Adapted from rs2967605 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.