rs2981582(A;G)

1.3x higher risk of ER+ breast cancer

Magnitude
3.0Important
Repute
Bad
Frequency
48%Average of 11 populations
On SNPedia
rs2981582(C;T)Minus strand
Gene
FGFR2

Frequency

Share of people with A;G in each HapMap population.

  • African ancestry (Southwest US)63%
  • Luhya (Kenya)58%
  • Maasai (Kenya)52%
  • Yoruba (Nigeria)51%
  • Gujarati Indian51%
  • Mexican ancestry (Los Angeles)47%
  • Chinese (Denver)44%
  • Tuscan43%
  • European ancestry (Utah)42%
  • Han Chinese (Beijing)41%
  • Japanese (Tokyo)38%

Other genotypes of rs2981582

  1. G;GGoodnormalTypical · 0.034% of people
  2. A;AMost notableBad1.7x higher risk of ER+ breast cancerImportant · 3.217% of people

All about rs2981582

Source and license

Adapted from rs2981582(C;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.