rs3008052

A SNP in the PDE10A gene on chromosome 6. Its most notable genotype is C;C: common/normal

Gene
PDE10A
Location
Chr 6165,653,494 (GRCh38)
Highest magnitude
0.0Typical
Tested on
FamilyTreeDNA

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableGoodcommon/normalTypical · 0.068% of people

On SNPedia: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 68%
  • European ancestry (Utah)C;C 51%
  • Han Chinese (Beijing)C;C 96%
  • Japanese (Tokyo)C;C 96%
  • Yoruba (Nigeria)C;C 73%
  • African ancestry (Southwest US)C;C 67%
  • Chinese (Denver)C;C 96%
  • Gujarati IndianC;C 54%
  • Luhya (Kenya)C;C 58%
  • Mexican ancestry (Los Angeles)C;C 70%
  • Maasai (Kenya)C;C 47%
  • TuscanC;C 46%

Other PDE10A SNPs

All PDE10A SNPs

Notes

From SNPedia

Notes

rs3008052(T), the minor allele for this SNP located in the PDE10A gene on chromosome 6, has been reported to be associated with increased thyroxine [T4] levels and larger spleen size in the indigenous Bajau people (“Sea Nomads”) of Southeast Asia, who live a subsistence lifestyle based on breath-hold diving and are renowned for their extraordinary breath-holding abilities. The association is statistically significant but not deterministic.

Source and license

Adapted from rs3008052 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.