rs3092891

A SNP in the RB1 gene on chromosome 13. Its most notable genotype is C;T: Retinoblastoma (predicted)

Gene
RB1
Location
Chr 1348,379,594 (GRCh38)
Highest magnitude
6.8Very important
Tested on
23andMe, AncestryDNA

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CGoodcommon in clinvarTypical · 0.0100% of people
  2. C;TMost notableBadRetinoblastoma (predicted)Very important · 6.80% of people

On SNPedia: (C;C), (C;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 4 HapMap populations.

  • AverageC;C 100% C;T 0%
  • European ancestry (Utah)C;C 100% C;T 0%
  • Han Chinese (Beijing)C;C 100% C;T 0%
  • Japanese (Tokyo)C;C 100% C;T 0%
  • Yoruba (Nigeria)C;C 100% C;T 0%

Other RB1 SNPs

All RB1 SNPs

Source and license

Adapted from rs3092891 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.