rs309375

A SNP on chromosome 4. Its most notable genotype is C;C: Smaller mosquito bites

Gene
None listed
Location
Chr 4122,760,001 (GRCh38)
Highest magnitude
1.5Minor
Tested on
23andMe
Minor allele frequency
23%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. C;CMost notableGoodSmaller mosquito bitesMinor · 1.54% of people
  2. A;CNot ratedAverage mosquito bitesMinor · 1.119% of people
  3. A;ABadLarger mosquito bitesMinor · 1.578% of people

SNPedia records rs309375 on the minus strand: (G;G), (G;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 4% A;C 19% A;A 78%
  • European ancestry (Utah)C;C 18% A;C 49% A;A 34%
  • Han Chinese (Beijing)C;C 2% A;C 12% A;A 86%
  • Japanese (Tokyo)C;C 0% A;C 7% A;A 93%
  • Yoruba (Nigeria)C;C 0% A;C <1% A;A 99%
  • African ancestry (Southwest US)C;C 0% A;C 18% A;A 83%
  • Chinese (Denver)C;C 0% A;C 13% A;A 87%
  • Gujarati IndianC;C 5% A;C 18% A;A 77%
  • Luhya (Kenya)C;C 0% A;C <1% A;A 99%
  • Mexican ancestry (Los Angeles)C;C 5% A;C 38% A;A 57%
  • Maasai (Kenya)C;C 0% A;C 3% A;A 97%
  • TuscanC;C 13% A;C 45% A;A 42%

Notes

From SNPedia

Notes

http://blog.23andme.com/23andme-research/bug-bite-genetics/ mosquito bite size

Source and license

Adapted from rs309375 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.