rs3118470
A SNP in the IL2RA gene on chromosome 10. Its most notable genotype is T;T.
- Gene
- IL2RA
- Location
- Chr 106,059,750 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 32%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageT;T 53%
- European ancestry (Utah)T;T 49%
- Han Chinese (Beijing)T;T 22%
- Japanese (Tokyo)T;T 34%
- Yoruba (Nigeria)T;T 80%
- African ancestry (Southwest US)T;T 75%
- Chinese (Denver)T;T 28%
- Gujarati IndianT;T 34%
- Luhya (Kenya)T;T 69%
- Mexican ancestry (Los Angeles)T;T 59%
- Maasai (Kenya)T;T 72%
- TuscanT;T 59%
Related
Notes
From SNPedia
Show notes, about 120 words
rs3118470 increases susceptibility to Type I Diabetes 1.28 times for carriers of the C allele Impact of diabetes susceptibility loci on progression from pre-diabetes to diabetes in at-risk individuals of the diabetes prevention trial-type 1 (DPT-1). Joint genetic susceptibility to type 1 diabetes and autoimmune thyroiditis: from epidemiology to mechanisms. Follow-up analysis of genome-wide association data identifies novel loci for type 1 diabetes. Genetic association between the interleukin-2 receptor-alpha gene and mode of onset of type 1 diabetes in the Japanese population. Overview of the Rapid Response data. Analysis of 19 genes for association with type I diabetes in the Type I Diabetes Genetics Consortium families.
Source and license
Adapted from rs3118470 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.