rs3135388(G;G)

Normal

Magnitude
0.0Typical
Repute
Good
Frequency
91%Average of 11 populations
On SNPedia
rs3135388(C;C)Minus strand
Gene
HLA-DRA

Frequency

Share of people with G;G in each HapMap population.

  • Japanese (Tokyo)100%
  • Chinese (Denver)99%
  • Han Chinese (Beijing)96%
  • Gujarati Indian96%
  • Maasai (Kenya)96%
  • Yoruba (Nigeria)94%
  • African ancestry (Southwest US)93%
  • Luhya (Kenya)93%
  • Mexican ancestry (Los Angeles)88%
  • Tuscan84%
  • European ancestry (Utah)66%

Other genotypes of rs3135388

  1. A;GBad3x higher risk of multiple sclerosisMinor · 1.88% of people
  2. A;AMost notableBad3-6x higher risk of multiple sclerosisWorth knowing · 2.0<1% of people

All about rs3135388

Notes

From SNPedia

Rs3135388(C;C) is highly correlated with the HLA-DRB1*1501 allele. There is no additional risk of multiple sclerosis associated with the (C;C) genotype.

Source and license

Adapted from rs3135388(C;C) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.