rs334348
A SNP in the TGFBR1 gene on chromosome 9. Its most notable genotype is A;A: common in clinvar
- Gene
- TGFBR1
- Location
- Chr 999,150,189 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 34%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageA;A 42%
- European ancestry (Utah)A;A 58%
- Han Chinese (Beijing)A;A 29%
- Japanese (Tokyo)A;A 24%
- Yoruba (Nigeria)A;A 50%
- African ancestry (Southwest US)A;A 42%
- Chinese (Denver)A;A 28%
- Gujarati IndianA;A 40%
- Luhya (Kenya)A;A 49%
- Mexican ancestry (Los Angeles)A;A 52%
- Maasai (Kenya)A;A 42%
- TuscanA;A 51%
Related
Conditions, medicines and genes
Other TGFBR1 SNPs
- rs111426349C;TLoeys-Dietz SyndromeVery important
- rs113605875A;GLoeys-Dietz SyndromeVery important
- rs121918710G;TLoeys-Dietz SyndromeVery important
- rs121918711A;GLoeys-Dietz SyndromeVery important
- rs121918712C;TLoeys-Dietz SyndromeVery important
- rs121918713G;TLoeys-Dietz SyndromeVery important
- rs730880223A;GLoeys-Dietz SyndromeVery important
- rs863223829-;AAGLoeys-Dietz SyndromeVery important
Notes
From SNPedia
Notes
appears relevant to colon cancer rs334348, rs334349 and rs1590 (in total linkage disequilibrium with each other) and a fourth marker, rs7871490
Source and license
Adapted from rs334348 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.