rs339097
A SNP in the CALU gene on chromosome 7. Its most notable genotype is A;A: common in complete genomics
- Gene
- CALU
- Location
- Chr 7128,759,170 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 5%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs339097 on the minus strand: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 8 HapMap populations.
- AverageA;A 86%
- European ancestry (Utah)A;A 100%
- Han Chinese (Beijing)A;A 98%
- Japanese (Tokyo)A;A 99%
- Yoruba (Nigeria)A;A 67%
- African ancestry (Southwest US)A;A 72%
- Chinese (Denver)A;A 98%
- Luhya (Kenya)A;A 69%
- Maasai (Kenya)A;A 81%
Related
Conditions, medicines and genes
Notes
From SNPedia
Notes
PharmGKB indicates that this SNP is relevant to Warfarin dosing. rs339097(G) is associated with 14.5% higher therapeutic warfarin dose in African Americans. This variant is also more common in African Americans with minor allele frequencies of 11–14% , but only 0.2% in Caucasians. Genetic and nongenetic factors associated with warfarin dose requirements in Egyptian patients.
Source and license
Adapted from rs339097 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.