rs35753505

A SNP on chromosome 8. Its most notable genotype is C;C.

Gene
None listed
Location
Chr 831,616,625 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
35%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableNot ratedNo summary available.Worth knowing · 2.0
  2. T;TNot ratedNo summary available.Typical · 0.0

On SNPedia: (C;C), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Conditions, medicines and genes

Notes

From SNPedia

Show notes, about 130 words

Rs35753505 (SNP8NRG221533) is located within the 5'-flanking region of the NRG1 (Neuregulin 1) gene. g2b2mh blog rs35753505(C;C) correlates with frontal brain having to working harder during a working memory task. personality traits - C allele carriers associated with higher (NEO-FFI) scores of neuroticism and lower scores of conscientiousness in a sample of 523 healthy individuals The results suggest that subjects with risk alleles show hyperactivations in areas associated with elaborate episodic memory encoding and retrieval strategies.

C;C

frontal brain having to working harder during a working memory task. higher scores of neuroticism and lower scores of conscientiousness hyperactivations in areas associated with elaborate episodic memory encoding and retrieval strategies.

Source and license

Adapted from rs35753505 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.