rs357564
A SNP in the PTCH1 gene on chromosome 9. Its most notable genotype is G;G: common in clinvar
- Gene
- PTCH1
- Location
- Chr 995,447,312 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 38%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 4 HapMap populations.
- AverageG;G 34%
- European ancestry (Utah)G;G 52%
- Han Chinese (Beijing)G;G 21%
- Japanese (Tokyo)G;G 7%
- Yoruba (Nigeria)G;G 54%
Related
Other PTCH1 SNPs
- rs199476090A;GBasal cell nevus syndromeVery important
- rs766313615A;GBasal cell nevus syndromeVery important
- rs778260156G;TBasal cell nevus syndromeVery important
- rs786204056A;GBasal cell nevus syndromeVery important
- rs863224442C;TBasal cell nevus syndromeVery important
- rs863224443C;TBasal cell nevus syndromeVery important
- rs863224444C;TBasal cell nevus syndromeVery important
- rs863224484-;CPossible miscall in 23andMe and Ancestry data; otherwise, Basal cell nevus syndromeVery important
Notes
From SNPedia
Notes
PTCH1 gene haplotype association with basal cell carcinoma after transplantation. Follow-up association studies of chromosome region 9q and nonsyndromic cleft lip/palate.
Source and license
Adapted from rs357564 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.