rs3731566
A SNP in the ADD3 gene on chromosome 10. Its most notable genotype is A;A: normal
- Gene
- ADD3
- Location
- Chr 10110,126,331 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 19%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 3 HapMap populations.
- AverageA;A 100% A;G 0% G;G 0%
- Han Chinese (Beijing)A;A 100% A;G 0% G;G 0%
- Japanese (Tokyo)A;A 100% A;G 0% G;G 0%
- Yoruba (Nigeria)A;A 100% A;G 0% G;G 0%
Notes
From SNPedia
Notes
rs3731566 is a SNP in the adducin 3 ADD3 gene. This variation on its own has not been linked to hypertension. However, carriers of a rs4961(T) SNP (a SNP in the ADD1 gene) who also happen to be rs3731566(G;G) homozgyotes are found to have higher blood pressure (by about 8 mmHg) than if they are carriers of one or more rs3731566(A) alleles.
Source and license
Adapted from rs3731566 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.