rs3734353

A SNP in the SIM1 gene on chromosome 6. Its most notable genotype is T;T: common in clinvar

Gene
SIM1
Location
Chr 6100,448,693 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe
Minor allele frequency
35%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TMost notableGoodcommon in clinvarTypical · 0.049% of people

SNPedia records rs3734353 on the minus strand: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageT;T 49%
  • European ancestry (Utah)T;T 43%
  • Han Chinese (Beijing)T;T 39%
  • Japanese (Tokyo)T;T 29%
  • Yoruba (Nigeria)T;T 55%
  • African ancestry (Southwest US)T;T 63%
  • Chinese (Denver)T;T 38%
  • Gujarati IndianT;T 66%
  • Luhya (Kenya)T;T 62%
  • Mexican ancestry (Los Angeles)T;T 40%
  • Maasai (Kenya)T;T 58%
  • TuscanT;T 47%

Other SIM1 SNPs

All SIM1 SNPs

Source and license

Adapted from rs3734353 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.