rs3735684

A SNP in the CYP2W1 gene on chromosome 7. Its most notable genotype is A;G: associated with increased colorectal cancer risk

Gene
CYP2W1
Location
Chr 7985,219 (GRCh38)
Highest magnitude
1.0Minor
Tested on
23andMe
Minor allele frequency
6%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GGoodcommon in complete genomicsTypical · 0.099% of people
  2. A;GMost notableBadassociated with increased colorectal cancer riskMinor · 1.0<1% of people
  3. A;ABadassociated with increased colorectal cancer riskMinor · 1.00% of people

SNPedia records rs3735684 on the minus strand: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 4 HapMap populations.

  • AverageG;G 99% A;G <1% A;A 0%
  • European ancestry (Utah)G;G 99% A;G 2% A;A 0%
  • Han Chinese (Beijing)G;G 100% A;G 0% A;A 0%
  • Japanese (Tokyo)G;G 100% A;G 0% A;A 0%
  • Yoruba (Nigeria)G;G 98% A;G 2% A;A 0%

Source and license

Adapted from rs3735684 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.