rs3735972
A SNP in the CNGB3 gene on chromosome 8. Its most notable genotype is C;C.
- Gene
- CNGB3
- Location
- Chr 886,575,970 (GRCh38)
- Highest magnitude
- 1.5Minor
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 8%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
- T;TGoodcommon in complete genomics
- C;CMost notableNot ratedNo summary available.
- A;ANot ratedNo summary available.
SNPedia records rs3735972 on the minus strand: (A;A), (G;G), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageT;T 88% C;C <1% A;A 0%
- European ancestry (Utah)T;T 84% C;C 0% A;A 0%
- Han Chinese (Beijing)T;T 88% C;C 0% A;A 0%
- Japanese (Tokyo)T;T 76% C;C 4% A;A 0%
- Yoruba (Nigeria)T;T 88% C;C 0% A;A 0%
- African ancestry (Southwest US)T;T 90% C;C 0% A;A 0%
- Chinese (Denver)T;T 93% C;C <1% A;A 0%
- Gujarati IndianT;T 91% C;C 0% A;A 0%
- Luhya (Kenya)T;T 94% C;C 0% A;A 0%
- Mexican ancestry (Los Angeles)T;T 88% C;C 2% A;A 0%
- Maasai (Kenya)T;T 92% C;C <1% A;A 0%
- TuscanT;T 87% C;C 1% A;A 0%
Related
Notes
From SNPedia
Notes
rs3735972, also known as E755G or Glu755Gly, is a SNP in the cyclic nucleotide gated-channel beta 3 CNGB3 gene. Although this SNP causes an amino acid substitution, it is not known to have medical consequences, unlike some other SNPs in this same gene which are known to lead to various forms of color-blindness.
C;C
Rare, but observed with no apparent consequences.
Source and license
Adapted from rs3735972 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.