rs3741559

A SNP in the AQP2 gene on chromosome 12. Its most notable genotype is G;G: common in clinvar

Gene
AQP2
Location
Chr 1249,951,193 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
20%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. G;GMost notableGoodcommon in clinvarTypical · 0.062% of people

On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageG;G 62%
  • European ancestry (Utah)G;G 74%
  • Han Chinese (Beijing)G;G 37%
  • Japanese (Tokyo)G;G 45%
  • Yoruba (Nigeria)G;G 83%
  • African ancestry (Southwest US)G;G 72%
  • Chinese (Denver)G;G 39%
  • Gujarati IndianG;G 47%
  • Luhya (Kenya)G;G 76%
  • Mexican ancestry (Los Angeles)G;G 83%
  • Maasai (Kenya)G;G 64%
  • TuscanG;G 62%

Other AQP2 SNPs

All AQP2 SNPs

Notes

From SNPedia

Notes

Candidate gene study to investigate the genetic determinants of normal variation in central corneal thickness.

Source and license

Adapted from rs3741559 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.