rs3741981

A SNP in the OAS1 gene on chromosome 12. Its most notable genotype is A;G.

Gene
OAS1
Location
Chr 12112,911,065 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, FamilyTreeDNA

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;GMost notableNot ratedNo summary available.Typical · 0.040% of people

On SNPedia: (G;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;G 40%
  • European ancestry (Utah)A;G 53%
  • Han Chinese (Beijing)A;G 45%
  • Japanese (Tokyo)A;G 49%
  • Yoruba (Nigeria)A;G 19%
  • African ancestry (Southwest US)A;G 39%
  • Chinese (Denver)A;G 51%
  • Gujarati IndianA;G 50%
  • Luhya (Kenya)A;G 17%
  • Mexican ancestry (Los Angeles)A;G 41%
  • Maasai (Kenya)A;G 28%
  • TuscanA;G 54%

Conditions, medicines and genes

Other OAS1 SNPs

All OAS1 SNPs

Notes

From SNPedia

Notes

Was investigated for a diabetes association, but seemed to have none. suggests it or a neighbor may be involved in multiple sclerosis

Source and license

Adapted from rs3741981 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.