rs3745516(A;A)

Increased risk of developing primary biliary cirrhosis

Magnitude
2.0Worth knowing
Repute
Bad
Frequency
40%Average of 11 populations
On SNPedia
rs3745516(A;A)
Gene
SPIB

Frequency

Share of people with A;A in each HapMap population.

  • Japanese (Tokyo)73%
  • Chinese (Denver)67%
  • Han Chinese (Beijing)53%
  • Yoruba (Nigeria)53%
  • Maasai (Kenya)49%
  • African ancestry (Southwest US)47%
  • Luhya (Kenya)43%
  • Mexican ancestry (Los Angeles)26%
  • Gujarati Indian13%
  • Tuscan6%
  • European ancestry (Utah)5%

Other genotypes of rs3745516

  1. A;GBadSlightly increased risk of developing primary biliary cirrhosisMinor · 1.539% of people
  2. G;GGoodNormal risk of developing primary biliary cirrhosisMinor · 1.022% of people

All about rs3745516

Source and license

Adapted from rs3745516(A;A) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.