rs3790844

A SNP in the NR5A2 gene on chromosome 1. Its most notable genotype is G;G: reduced risk (0.59x) of pancreatic cancer

Gene
NR5A2
Location
Chr 1200,038,304 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA
Minor allele frequency
35%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GMost notableGoodreduced risk (0.59x) of pancreatic cancerWorth knowing · 2.017% of people
  2. A;GGoodslightly reduced risk (0.77x) for pancreatic cancerMinor · 1.533% of people
  3. A;ANot ratedcommon/normalTypical · 0.049% of people

SNPedia records rs3790844 on the minus strand: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageG;G 17% A;G 33% A;A 49%
  • European ancestry (Utah)G;G 4% A;G 35% A;A 61%
  • Han Chinese (Beijing)G;G 43% A;G 48% A;A 9%
  • Japanese (Tokyo)G;G 45% A;G 44% A;A 11%
  • Yoruba (Nigeria)G;G 0% A;G 11% A;A 89%
  • African ancestry (Southwest US)G;G 2% A;G 25% A;A 74%
  • Chinese (Denver)G;G 47% A;G 42% A;A 11%
  • Gujarati IndianG;G 23% A;G 50% A;A 28%
  • Luhya (Kenya)G;G 2% A;G 21% A;A 77%
  • Mexican ancestry (Los Angeles)G;G 19% A;G 38% A;A 43%
  • Maasai (Kenya)G;G 1% A;G 19% A;A 80%
  • TuscanG;G 3% A;G 35% A;A 62%

Conditions, medicines and genes

Notes

From SNPedia

Notes

23andMe reports that the G allele of this SNP appears to lower the risk of pancreatic cancer. Genome-wide association study of pancreatic cancer in Japanese population.

Source and license

Adapted from rs3790844 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.