rs3829241

A SNP in the TPCN2 gene on chromosome 11. Its most notable genotype is G;G: common in clinvar

Gene
TPCN2
Location
Chr 1169,087,895 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
24%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. G;GMost notableGoodcommon in clinvarTypical · 0.070% of people

On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageG;G 70%
  • European ancestry (Utah)G;G 33%
  • Han Chinese (Beijing)G;G 66%
  • Japanese (Tokyo)G;G 57%
  • Yoruba (Nigeria)G;G 97%
  • African ancestry (Southwest US)G;G 86%
  • Chinese (Denver)G;G 65%
  • Gujarati IndianG;G 81%
  • Luhya (Kenya)G;G 94%
  • Mexican ancestry (Los Angeles)G;G 54%
  • Maasai (Kenya)G;G 94%
  • TuscanG;G 41%

Other TPCN2 SNPs

All TPCN2 SNPs

Notes

From SNPedia

Notes

This SNP influences appearance and is located in the TPCN2 gene. A study of 5130 Icelanders (with further followup in another 2116 Icelanders and 1214 Dutch individuals) found significant association between a group of SNPs within the TPCN2 gene.All of the discovered difference between blonde and brown hair could be explained by genotypes with rs3829241 and Rs35264875. The A allele was significantly associated with blonde versus brown hair with a P-value 6.2e-16 Summaried in gnxp

Source and license

Adapted from rs3829241 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.