rs3918290(C;T)

Some 5-fluorouracil toxicity, dihydropyrimidine dehydrogenase deficiency carrier

Magnitude
3.0Important
Repute
Bad
Frequency
<1%Average of 7 populations
On SNPedia
rs3918290(A;G)Minus strand
Gene
DPYD

Frequency

Share of people with C;T in each HapMap population.

  • Gujarati Indian3%
  • African ancestry (Southwest US)2%
  • Tuscan1%
  • European ancestry (Utah)<1%
  • Han Chinese (Beijing)0%
  • Japanese (Tokyo)0%
  • Yoruba (Nigeria)0%

Other genotypes of rs3918290

  1. T;TMost notableBad5-fluorouracil toxicity, dihydropyrimidine dehydrogenase deficiencyImportant · 3.50% of people
  2. C;CGoodcommon in complete genomicsTypical · 0.099% of people

All about rs3918290

Notes

From SNPedia

You can expect some toxicity from 5-fluorouracil, a common treatment for various cancers. This variation does not influence your risk of cancer.

Source and license

Adapted from rs3918290(A;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.