rs3923809(G;G)

Normal risk of developing restless legs syndrome

Magnitude
1.0Minor
Repute
Good
Frequency
17%Average of 11 populations
On SNPedia
rs3923809(G;G)
Gene
BTBD9

Frequency

Share of people with G;G in each HapMap population.

  • Japanese (Tokyo)41%
  • Han Chinese (Beijing)40%
  • Chinese (Denver)32%
  • Gujarati Indian21%
  • Mexican ancestry (Los Angeles)19%
  • Yoruba (Nigeria)10%
  • African ancestry (Southwest US)9%
  • Tuscan6%
  • European ancestry (Utah)5%
  • Luhya (Kenya)5%
  • Maasai (Kenya)5%

Other genotypes of rs3923809

  1. A;AMost notableBad1.9x risk for developing restless legs syndromeWorth knowing · 2.038% of people
  2. A;GBadSlightly increased risk of developing restless legs syndromeMinor · 1.545% of people

All about rs3923809

Notes

From SNPedia

rs3923809 is a A/G variation on human chromosome 6. Associated with: Restless legs syndrome. This SNP, located in an intron of the BTBD9 gene, has a variant that is seen somewhat more frequently in individuals with restless legs syndrome. The risk allele is rs3923809(A); carriers of two such alleles, i.e. those with rs3923809(A;A) genotypes, are estimated to be 1.9 fold more likely to have restless legs syndrome than rs3923809(G;G) individuals. The authors of this study suggest that perhaps half of the cases of restless legs syndrome may involve the rs3923809 risk genotypes. Consistent with this finding, another report about rs3923809 links the (G) minor allele to a lower frequency of restless legs syndrome with an overall odds ratio of 0.57 (CI: 0.48-0.68).

References

Source and license

Adapted from rs3923809(G;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.