rs393548

A SNP in the IL12RB1 gene on chromosome 19. Its most notable genotype is T;T: common in clinvar

Gene
IL12RB1
Location
Chr 1918,086,934 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe
Minor allele frequency
19%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. T;TMost notableGoodcommon in clinvarTypical · 0.061% of people

On SNPedia: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 4 HapMap populations.

  • AverageT;T 61%
  • European ancestry (Utah)T;T 60%
  • Han Chinese (Beijing)T;T 76%
  • Japanese (Tokyo)T;T 54%
  • Yoruba (Nigeria)T;T 55%

Other IL12RB1 SNPs

All IL12RB1 SNPs

Source and license

Adapted from rs393548 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.