rs4129009

A SNP in the TLR10 gene on chromosome 4. Its most notable genotype is T;T: common in complete genomics

Gene
TLR10
Location
Chr 438,773,268 (GRCh38)
Highest magnitude
0.0Typical
Tested on
FamilyTreeDNA
Minor allele frequency
19%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TMost notableGoodcommon in complete genomicsTypical · 0.062% of people

SNPedia records rs4129009 on the minus strand: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 9 HapMap populations.

  • AverageT;T 62%
  • European ancestry (Utah)T;T 65%
  • Han Chinese (Beijing)T;T 38%
  • Japanese (Tokyo)T;T 23%
  • African ancestry (Southwest US)T;T 89%
  • Chinese (Denver)T;T 47%
  • Gujarati IndianT;T 68%
  • Mexican ancestry (Los Angeles)T;T 83%
  • Maasai (Kenya)T;T 95%
  • TuscanT;T 48%

Other TLR10 SNPs

All TLR10 SNPs

Notes

From SNPedia

Notes

Toll-like receptor signaling pathway variants and prostate cancer mortality. Genetic variants and prostate cancer risk: candidate replication and exploration of viral restriction genes. Sequence variants in the TLR4 and TLR6-1-10 genes and prostate cancer risk. Results based on pooled analysis from three independent studies. Association between toll-like receptor 10 (TLR10) gene polymorphisms and childhood IgA nephropathy. Association of polymorphisms in TLR genes and in genes of the Toll-like receptor signaling pathway with cancer risk. Association between C13ORF31, NOD2, RIPK2 and TLR10 polymorphisms and urothelial bladder cancer.

Source and license

Adapted from rs4129009 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.