rs421262
A SNP in the GALC gene on chromosome 14. Its most notable genotype is C;C: common in complete genomics
- Gene
- GALC
- Location
- Chr 1487,934,869 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 6%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (C;C), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 4 HapMap populations.
- AverageC;C 81% T;T 2%
- European ancestry (Utah)C;C 100% T;T 0%
- Han Chinese (Beijing)C;C 89% T;T 0%
- Japanese (Tokyo)C;C 81% T;T 2%
- Yoruba (Nigeria)C;C 56% T;T 7%
Related
Other GALC SNPs
- rs121908010A;AKrabbe disease (likely)Very important
- rs199847983T;TKrabbe disease (likely)Very important
- rs200378205T;TKrabbe disease (likely)Very important
- rs374635469T;TKrabbe diseaseVery important
- rs387906952T;TKrabbe disease (likely)Very important
- rs387906953C;CKrabbe disease (likely)Very important
- rs387906954C;CKrabbe disease (likely)Very important
- rs387906955T;TKrabbe disease (likely)Very important
Source and license
Adapted from rs421262 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.