rs4242182

A SNP in the MSX2 gene on chromosome 5. Its most notable genotype is C;C.

Gene
MSX2
Location
Chr 5174,729,165 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
21%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableNot ratedNo summary available.Typical · 0.061% of people
  2. T;TGoodcommon in clinvarTypical · 0.014% of people

On SNPedia: (C;C), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 61% T;T 14%
  • European ancestry (Utah)C;C 79% T;T 2%
  • Han Chinese (Beijing)C;C 99% T;T 0%
  • Japanese (Tokyo)C;C 95% T;T 0%
  • Yoruba (Nigeria)C;C 11% T;T 50%
  • African ancestry (Southwest US)C;C 25% T;T 30%
  • Chinese (Denver)C;C 95% T;T <1%
  • Gujarati IndianC;C 89% T;T 1%
  • Luhya (Kenya)C;C 10% T;T 43%
  • Mexican ancestry (Los Angeles)C;C 74% T;T 0%
  • Maasai (Kenya)C;C 20% T;T 28%
  • TuscanC;C 73% T;T 3%

Source and license

Adapted from rs4242182 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.