rs42524

A SNP in the COL1A2 gene on chromosome 7. Its most notable genotype is C;C: common in clinvar

Gene
COL1A2
Location
Chr 794,413,927 (GRCh38)
Highest magnitude
0.0Typical
Tested on
AncestryDNA, FamilyTreeDNA
Minor allele frequency
15%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableGoodcommon in clinvarTypical · 0.02% of people

On SNPedia: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 4 HapMap populations.

  • AverageC;C 2%
  • European ancestry (Utah)C;C 9%
  • Han Chinese (Beijing)C;C 0%
  • Japanese (Tokyo)C;C 0%
  • Yoruba (Nigeria)C;C 0%

Other COL1A2 SNPs

All COL1A2 SNPs

Notes

From SNPedia

Notes

rs42524 is a SNP in the COL1A2 gene. This SNP has been associated with familial intracranial aneurysms (IA) in both Japanese and Chinese populations; in Chinese patients, the odds ratio is 2.579 (CI: 1.48-4.47).

Source and license

Adapted from rs42524 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.