rs4253132

A SNP in the ERCC6 gene on chromosome 10. Its most notable genotype is G;G: common in clinvar

Gene
ERCC6
Location
Chr 1049,493,110 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
13%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GMost notableGoodcommon in clinvarTypical · 0.05% of people

SNPedia records rs4253132 on the minus strand: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 10 HapMap populations.

  • AverageG;G 5%
  • European ancestry (Utah)G;G <1%
  • Han Chinese (Beijing)G;G 0%
  • Japanese (Tokyo)G;G 0%
  • Yoruba (Nigeria)G;G 13%
  • African ancestry (Southwest US)G;G 14%
  • Gujarati IndianG;G 2%
  • Luhya (Kenya)G;G 12%
  • Mexican ancestry (Los Angeles)G;G 0%
  • Maasai (Kenya)G;G 9%
  • TuscanG;G 0%

Other ERCC6 SNPs

All ERCC6 SNPs

Source and license

Adapted from rs4253132 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.