rs4409764

A SNP on chromosome 10. Its most notable genotype is G;G: normal risk of Crohn's disease

Gene
None listed
Location
Chr 1099,524,480 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
49%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. G;GMost notableGoodnormal risk of Crohn's diseaseTypical · 0.025% of people
  2. G;TBad1.32x increased risk of Crohn's disease in KoreansTypical · 0.050% of people
  3. T;TBad>1.32x increased risk of Crohn's disease in KoreansTypical · 0.025% of people

On SNPedia: (G;G), (G;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageG;G 25% G;T 50% T;T 25%
  • European ancestry (Utah)G;G 32% G;T 45% T;T 23%
  • Han Chinese (Beijing)G;G 29% G;T 49% T;T 22%
  • Japanese (Tokyo)G;G 27% G;T 50% T;T 23%
  • Yoruba (Nigeria)G;G 20% G;T 50% T;T 30%
  • African ancestry (Southwest US)G;G 12% G;T 56% T;T 32%
  • Chinese (Denver)G;G 28% G;T 47% T;T 26%
  • Gujarati IndianG;G 36% G;T 50% T;T 15%
  • Luhya (Kenya)G;G 12% G;T 52% T;T 36%
  • Mexican ancestry (Los Angeles)G;G 38% G;T 47% T;T 16%
  • Maasai (Kenya)G;G 18% G;T 55% T;T 28%
  • TuscanG;G 23% G;T 52% T;T 26%

Notes

From SNPedia

Notes

Implicated in a 2015 Korean cohort for Crohn's disease. PMID 25489960

Source and license

Adapted from rs4409764 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.